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Molecular Hydrogen

TRUE WELLNESS STARTS WITH MOLECULAR HYDROGEN

 

It’s not just about hydration—it’s about delivering a clinically studied, bioavailable molecule that helps your body function at a higher level. With every sip of Kangen Water®, you’re not only hydrating, you’re fueling your body with one of nature’s most intelligent defenses against oxidative stress and modern cellular decline.

One of the most remarkable benefits of Kangen Water® lies in its high concentration of molecular hydrogen (H₂)—a tiny yet powerful antioxidant that is rapidly gaining recognition in the scientific and medical communities. Molecular hydrogen is the smallest and most bioavailable antioxidant in existence, allowing it to easily permeate cell membranes, mitochondria, and even the blood-brain barrier to combat oxidative stress at its source.

Unlike antioxidant supplements or artificially enhanced waters, Kangen Water® produces molecular hydrogen naturally during the electrolysis process. As hydrogen ions (H⁺) bond to form H₂ gas, no additives, tablets, or chemical reactions are required—just pure science and precise engineering. This gives the water its therapeutic potential and distinguishes it from every other type of drinking water available today.

Studies have linked molecular hydrogen to reduced inflammation, improved cognitive function, enhanced energy and recovery, better metabolic health, and protection against free radical damage. Backed by science, molecular hydrogen supports the body’s natural healing processes and longevity pathways, making it one of the most promising wellness innovations of our time.

Research Library

Molecular hydrogen is one of the most promising and rapidly expanding frontiers in wellness research, with over 1,500 peer-reviewed studies and growing clinical interest worldwide. Below, you’ll find a curated selection of these studies, showcasing the therapeutic potential of molecular hydrogen—from anxiety, mood, and stress to cancer, diabetes, and more. This is just a glimpse into a fast-evolving field of clinical science that continues to confirm what many are already experiencing firsthand.

Brain & Neurological Health

Antioxidant & Brain-Protection: Anti-inflammatory and antitumor action of hydrogen via reactive oxygen species

https://pmc.ncbi.nlm.nih.gov/articles/PMC6096066/

Mood Disorders: Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life

https://pmc.ncbi.nlm.nih.gov/articles/PMC5806445/

Brain Health: Hydrogen-rich water protects against ischemic brain injury in rats by regulating calcium buffering proteins

https://pubmed.ncbi.nlm.nih.gov/25920370/

Brain Health: Hydrogen is neuroprotective against surgically induced brain injury

https://link.springer.com/article/10.1186/2045-9912-1-7#page-1

Brain Health: Molecular Hydrogen in Drinking Water Protects against Neurodegenerative Changes Induced by Traumatic Brain Injury

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108034

Brain Health: Hydrogen water reduces NSE, IL-6, and TNF-α levels in hypoxic-ischemic encephalopathy

https://www.degruyterbrill.com/document/doi/10.1515/med-2016-0072/html

Neurological disorders: Molecular Hydrogen as a Neuroprotective Agent

https://pmc.ncbi.nlm.nih.gov/articles/PMC5412697/

Mental Health: Molecular hydrogen increases resilience to stress in mice

https://pmc.ncbi.nlm.nih.gov/articles/PMC5575246/

Parkinson’s Disease: Pilot study of H₂ therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial

https://pubmed.ncbi.nlm.nih.gov/23400965/

Parkinson’s Disease: Positive effect of an electrolyzed reduced water on gut permeability, fecal microbiota and liver in an animal model of Parkinson’s disease

https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0223238

Multiple sclerosis: Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice

https://pubmed.ncbi.nlm.nih.gov/27138092/

Anti-Inflammation & Immune Support

Anti-inflammatory: Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis

https://medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-2-27

Anti-inflammatory: Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.

https://www.sciencedirect.com/science/article/abs/pii/S0764446901013506

Anti-inflammatory: Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults

https://pubmed.ncbi.nlm.nih.gov/32699287/

Rheumatoid arthritis: Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases

https://pubmed.ncbi.nlm.nih.gov/23859555/

Anti-inflammatory: Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model

https://pubmed.ncbi.nlm.nih.gov/20351628/

Anti-inflammatory and antitumor action of hydrogen via reactive oxygen species (also fits Brain Health)

https://pmc.ncbi.nlm.nih.gov/articles/PMC6096066/

 

Metabolic Health, Diabetes & Weight Management

Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance

https://pubmed.ncbi.nlm.nih.gov/19083400/

Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice

https://onlinelibrary.wiley.com/doi/full/10.1038/oby.2011.6

The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial

https://www.dovepress.com/the-effects-of-24-week-high-concentration-hydrogen-rich-water-on-body--peer-reviewed-fulltext-article-DMSO

Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome

https://pmc.ncbi.nlm.nih.gov/articles/PMC3679390/

Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome—An Open Label Pilot Study

https://pmc.ncbi.nlm.nih.gov/articles/PMC2831093/

Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice

https://pubmed.ncbi.nlm.nih.gov/16945392/

Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice

https://pubmed.ncbi.nlm.nih.gov/17268057/

Weight Loss: Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet

https://pmc.ncbi.nlm.nih.gov/articles/PMC5295108/

 

Heart & Cardiovascular Health

Prevention of cardiovascular diseases: Role of exercise, dietary interventions, obesity and smoking cessation

https://pmc.ncbi.nlm.nih.gov/articles/PMC2716237/

Hydrogen-containing saline attenuates doxorubicin-induced heart failure in rats

https://pubmed.ncbi.nlm.nih.gov/25158576/

Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration

https://pubmed.ncbi.nlm.nih.gov/22891787/

The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis

https://www.mdpi.com/1424-8247/16/2/142

Effects of hydrogen as adjuvant treatment for unstable angina

https://pmc.ncbi.nlm.nih.gov/articles/PMC8474983/

Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial

https://pmc.ncbi.nlm.nih.gov/articles/PMC7259729/

Athletic Performance & Muscle Health

Drinking hydrogen water enhances endurance and relieves psychometric fatigue: a randomized, double-blind, placebo-controlled study

https://pubmed.ncbi.nlm.nih.gov/31251888/

Effects of 7-day intake of hydrogen-rich water on physical performance of trained and untrained subjects

https://pubmed.ncbi.nlm.nih.gov/34079172/

Hydrogen Rich Water Improved Ventilatory, Perceptual and Lactate Responses to Exercise

https://pubmed.ncbi.nlm.nih.gov/31574544/

Molecular Hydrogen Mitigates Performance Decrement during Repeated Sprints in Professional Soccer Players

https://www.mdpi.com/2072-6643/14/3/508

 

Molecular hydrogen in sports medicine: new therapeutic perspectives

https://pubmed.ncbi.nlm.nih.gov/25525953/

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes

https://pmc.ncbi.nlm.nih.gov/articles/PMC3395574/

Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice

https://pmc.ncbi.nlm.nih.gov/articles/PMC6837388/

Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms

https://www.mdpi.com/2218-1989/14/10/537?utm_source=chatgpt.com

Hydrogen-rich water supplementation promotes muscle recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial

https://pmc.ncbi.nlm.nih.gov/articles/PMC11046232/?utm_source=chatgpt.com

Liver & Kidney Health

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors

https://pmc.ncbi.nlm.nih.gov/articles/PMC3231938/

Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B

https://pubmed.ncbi.nlm.nih.gov/24127924/

Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease

https://pubmed.ncbi.nlm.nih.gov/30982748/

The Effect of Adjuvant Therapy with Molecular Hydrogen on Endogenous Coenzyme Q10 Levels and Platelet Mitochondrial Bioenergetics in Patients with Non-Alcoholic Fatty Liver Disease

https://pmc.ncbi.nlm.nih.gov/articles/PMC10419858/#sec5-ijms-24-12477

Effects of oral intake of hydrogen water on liver fibrogenesis in mice

https://pubmed.ncbi.nlm.nih.gov/23682614/

Amelioration of fatigue in chronic dialysis patients with dialysis solution employing electrolyzed water containing molecular hydrogen and its association with autonomic function balance

https://rrtjournal.biomedcentral.com/articles/10.1186/s41100-021-00376-2

Cancer & Anti-Tumor Effects

Antitumor effects of nano-bubble hydrogen-dissol

ved water are enhanced by coexistent platinum colloid and the combined hyperthermia with apoptosis-like cell death

https://www.spandidos-publications.com/or/24/6/1463

Hydrogen-rich water exerts anti-tumor effects comparable to 5-fluorouracil in a colorectal cancer xenograft model

https://pmc.ncbi.nlm.nih.gov/articles/PMC8790422/

A Systematic Review of Molecular Hydrogen Therapy in Cancer Management

https://pmc.ncbi.nlm.nih.gov/articles/PMC10152878/

Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors

https://pmc.ncbi.nlm.nih.gov/articles/PMC3231938/

Skin, Hair, Oral and Eye Health

Effects of hydrogen-rich water bath on visceral fat and skin blotch, with boiling-resistant hydrogen bubbles

https://pmc.ncbi.nlm.nih.gov/articles/PMC6607864/

Positive Effects of hydrogen water on 2,4-dinitrochlorobenzene-induced atopic dermatitis in NC/Nga mice

https://pubmed.ncbi.nlm.nih.gov/25177031/

Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis

https://pmc.ncbi.nlm.nih.gov/articles/PMC4665424/

Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury

https://pubmed.ncbi.nlm.nih.gov/19834032/

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model

https://pubmed.ncbi.nlm.nih.gov/20847117/

Other Health Areas

Hearing Loss: Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs

https://pubmed.ncbi.nlm.nih.gov/20888392/

 

Lung health: Hydrogen water alleviates lung injury induced by one-lung ventilation

https://pubmed.ncbi.nlm.nih.gov/26182997/

Bone Health: Hydrogen water consumption prevents osteopenia in ovariectomized rats

https://pubmed.ncbi.nlm.nih.gov/23121335/

Hangover: Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats

https://pubmed.ncbi.nlm.nih.gov/19887722/

Gut Health: Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China

https://pmc.ncbi.nlm.nih.gov/articles/PMC6352569/

Gut Health Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water

https://pubmed.ncbi.nlm.nih.gov/15617863/

General Antioxidant Effects & Hydration

Anti-aging and Longevity: Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells

https://pubmed.ncbi.nlm.nih.gov/27477846/

Hydrogen Water: Extra Healthy or a Hoax?—A Systematic Review

https://www.mdpi.com/1422-0067/25/2/973

Antioxidant effects of continuous intake of electrolyzed hydrogen water in healthy adults

https://pmc.ncbi.nlm.nih.gov/articles/PMC9712568/

Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage

https://pubmed.ncbi.nlm.nih.gov/9169001/

Molecular hydrogen: A potential radioprotective agent

https://www.sciencedirect.com/science/article/pii/S0753332220307824

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